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Dec 012018
 
At the Ash Annual Meeting “463 Imetelstat Treatment Leads to Durable Transfusion Independence (TI) in RBC Transfusion-Dependent (TD), Non-Del(5q) Lower Risk MDS Relapsed/Refractory to Erythropoiesis-Stimulating Agent (ESA) Who Are Lenalidomide (LEN) and HMA Naive” is a scheduled presentations for Sunday, December 2, 2018: 4:30 PM (https://ash.confex.com/ash/2018/webprogram/Paper114877.html; obtained on 12-1-2018). The information included:

“SUMMARY / CONCLUSIONS:

In this cohort of 38 non-del(5q) LR-MDS patients with a high RBC transfusion burden who were ESA relapsed/refractory and naïve to LEN/HMA, single-agent imetelstat yielded a TI rate of 37%, with a median duration of 10 months and limited side effects. Durable responses were characterized by transfusion independence >24 weeks and accompanied by Hb rise. Updated data will be presented.”

 

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